Difference in Infectivity of Mycobacterium leprae from Patients in Immunosuppressed Mice
نویسندگان
چکیده
منابع مشابه
Effect of cryo preservation on Mycobacterium leprae growth in the footpads of non-immunosuppressed mice.
OBJECTIVE To investigate using the mouse footpad system, whether the use of cryopreservants help in retaining the viability of Mycobacterium leprae samples stored at three different temperatures of 4 degrees, -20 degrees and -70 degrees C for 30 days. DESIGN Biopsies from eight untreated lepromatous leprosy cases were homogenised and inoculated into footpads of normal Swiss White mice within ...
متن کاملTemperature optimum of Mycobacterium leprae in mice.
Shepard, Charles C. (Communicable Disease Center, Atlanta, Ga.). Temperature optimum of Mycobacterium leprae in mice. J. Bacteriol. 90:1271-1275. 1965.-Mycobacterium leprae multiplied most rapidly in foot pads of mice kept at an air temperature of 20 C. At air temperatures of 15 and 25 C, bacillary multiplication was slightly slower; at 10 and 30 C, distinctly slower; and at 4 and 35 C, no baci...
متن کاملAirborne infection with Mycobacterium leprae in mice.
Although the portal of entry and mode of spread of M. leprae in human leprosy are still uncertain, it is widely held that direct person-to-person skin contact is important. This assumption has ignored the fact that patients with highly bacilliferous leprosy have nasal as well as dermal infection and that, since M. leprae is shed predominantly from the nose, leprosy might be an airborne infectio...
متن کاملBactericidal action of dapsone against Mycobacterium leprae in mice.
Dapsone (4,4'-diaminodiphenylsulfone), incorporated into the mouse chow in a concentration of 0.1 g/100 g of diet, was administered for 1 week to mice in which Mycobacterium leprae had multiplied to the level of 10(6) organisms/footpad. M. leprae were harvested from these and also from control mice, diluted serially, and inoculated into additional mice. The organisms recovered from untreated mi...
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ژورنال
عنوان ژورنال: Japanese journal of leprosy
سال: 1981
ISSN: 0386-3980,2185-1360
DOI: 10.5025/hansen1977.50.1